en Treatment Original/Research Article <div style="text-align: justify;"><span style="font-size:11pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:120%"><span style="color:#231f20">Introduction: </span></span></span></b><span style="font-size:10.0pt"><span style="line-height:120%"><span style="color:#231f20">The present study evaluates the efficacy of the Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders (UP) for cancer patients when delivered in a group format.</span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:120%"><span style="color:#231f20">Materials and Methods:</span></span></span></b><span style="font-size:10.0pt"><span style="line-height:120%"><span style="color:#231f20"> A clinical sample of 38 patients with a cancer diagnosis was enrolled in a randomized control trial (RCT) involving up to 7 sessions of treatment. Patients were randomly assigned to receive treatment with the UP (n=18) and the control group (n=20). The participants in the pre-test and post-test were examined by the Beck Depression Inventory Second Edition (BDI-II), McGill Pain Questionnaire (MPQ), and Cognitive Emotion Regulation Questionnaire (CERQ).</span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:120%"><span style="color:#231f20">Results: </span></span></span></b><span style="font-size:10.0pt"><span style="line-height:120%"><span style="color:#231f20">The UP significantly reduced the rate of symptoms of Depression, Pain perception, and maladaptive strategies. Also, a significant increase was shown in adaptive strategies in comparison to participants in the control group</span></span></span><span style="font-size:10.0pt"><span style="line-height:120%"><span style="color:#231f20">.</span></span></span></span></span></span><br> <b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:#231f20">Conclusions:</span></span></span></b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:#231f20"> Results from this RCT provide additional evidence for the efficacy of the UP in reducing symptoms of depression, pain perception, and maladaptive strategies in patients with cancer. Also, this therapy can increase adaptive strategies among these patients.</span></span></span></div> Unified Protocol, Depression, Pain Perception, Cognitive emotion regulation, Cancer 0 0 http://mcijournal.com/browse.php?a_code=A-10-392-3&slc_lang=en&sid=1 Shima Yazdani shimayazdany73@gmail.com 10031947532846004274 10031947532846004274 No Department of Psychology, Faculty of Education and Psychology, Ferdowsi University of Mashhad, Mashhad, Iran Ali Mashhadi mashhadi@um.ac.ir 10031947532846004275 10031947532846004275 Yes Department of Psychology, Faculty of Education and Psychology, Ferdowsi University of Mashhad, Mashhad, Iran Imanollah Bigdeli ibigdeli@um.ac.ir 10031947532846004276 10031947532846004276 No Department of Psychology, Faculty of Education and Psychology, Ferdowsi University of Mashhad, Mashhad, Iran Soodabeh Shahid Sales shahidsaless@mums.ac.ir 10031947532846004277 10031947532846004277 No Cancer Research Center, Mashhad University of Medical Sciences, Mashhad, Iran