Multidisciplinary Cancer Investigation
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Volume 4, Issue 4 (Multidisciplinary Cancer Investigation 2020)
Multidiscip Cancer Investig 2020, 4(4): 1-5 |
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Taccogna S, Ienzi S, Amendola S, Ventura C, Chiapparino E, D'Angelo M, et al . The Usefulness of CytoFoam-Core in the Diagnosis of Thyroid Metastasis From Colon Cancer: A Case Report. Multidiscip Cancer Investig 2020; 4 (4) :1-5
URL: http://mcijournal.com/article-1-298-en.html
URL: http://mcijournal.com/article-1-298-en.html
Silvia Taccogna 
1, Sara Ienzi2 , Stefano Amendola3 , Claudio Ventura3 , Elena Chiapparino4 , Martina D'Angelo2 , Basilio Lippi5 , Margherita Guarino6
1, Sara Ienzi2 , Stefano Amendola3 , Claudio Ventura3 , Elena Chiapparino4 , Martina D'Angelo2 , Basilio Lippi5 , Margherita Guarino6
1- Anatomic Pathology Unit, Regina Apostolorum Hospital, Albano Laziale, Rome, Italy , staccogna@regianaapostolorum.it
2- Anatomic Pathology Unit, Regina Apostolorum Hospital, Albano Laziale, Rome, Italy
3- Section of Endocrinology and Diabetology, Jewish Hospital, Rome, Italy
4- Division of Medical Oncology, ‘S. Giovanni Evangelista’ Hospital, Tivoli, Rome, Italy
5- Diagnostic Unit, Jewish Hospital, Rome, Italy
6- Diagnostic Laboratory Unit, Jewish Hospital, Rome, Italy
2- Anatomic Pathology Unit, Regina Apostolorum Hospital, Albano Laziale, Rome, Italy
3- Section of Endocrinology and Diabetology, Jewish Hospital, Rome, Italy
4- Division of Medical Oncology, ‘S. Giovanni Evangelista’ Hospital, Tivoli, Rome, Italy
5- Diagnostic Unit, Jewish Hospital, Rome, Italy
6- Diagnostic Laboratory Unit, Jewish Hospital, Rome, Italy
Abstract: (2450 Views)
Introduction: We report a case of a 64-year old man with a history of colon carcinoma. He underwent fine-needle aspiration by CytoFoam-core and diagnosis of metastatic colon cancer to the thyroid gland.
Case presentation: In this case report, a solid thyroid nodule in the right lobe of a 64-year-old male was aspirated. The cytological smears showed a small group of atypical cells with the obvious nucleolus, necrosis, and atypical tall columnar cells. Since the patient had undergone surgery for rectal cancer at age 63, suspicion of metastasis from colon cancer was raised. This was corroborated by CytoFoam-core immunocytochemistry; showing a positive staining pattern for caudal type homeobox transcription factor 2 (cd×2) and cytokeratin 20 (CK20); while thyroglobulin (TG) and thyroid transcription factor-1 (TTF-1) were both negative.
Case presentation: In this case report, a solid thyroid nodule in the right lobe of a 64-year-old male was aspirated. The cytological smears showed a small group of atypical cells with the obvious nucleolus, necrosis, and atypical tall columnar cells. Since the patient had undergone surgery for rectal cancer at age 63, suspicion of metastasis from colon cancer was raised. This was corroborated by CytoFoam-core immunocytochemistry; showing a positive staining pattern for caudal type homeobox transcription factor 2 (cd×2) and cytokeratin 20 (CK20); while thyroglobulin (TG) and thyroid transcription factor-1 (TTF-1) were both negative.
Conclusion: The main objective was to correctly identify the metastatic thyroid
carcinoma (MTC) and exclude other clinical entities as primary diseases of the thyroid gland. Cytology plays a crucial role in the follow-up and the therapeutic management of the patients. The CytoFoam-core preparations were diagnostic of metastatic colon cancer to the thyroid gland. In this context, the CytoFoam-core could be of great help, especially in previous oncologic history cases.
carcinoma (MTC) and exclude other clinical entities as primary diseases of the thyroid gland. Cytology plays a crucial role in the follow-up and the therapeutic management of the patients. The CytoFoam-core preparations were diagnostic of metastatic colon cancer to the thyroid gland. In this context, the CytoFoam-core could be of great help, especially in previous oncologic history cases.
Select article type: Case Report and Series |
Subject:
Supportive and Palliative Care
Received: 2020/08/15 | Accepted: 2020/09/23 | ePublished: 2020/10/1
Received: 2020/08/15 | Accepted: 2020/09/23 | ePublished: 2020/10/1
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