Multidisciplinary Cancer Investigation
نشریه بین المللی چند تخصصی سرطان
Multidiscip Cancer Investig
Medical Sciences
http://mcijournal.com
1
admin
2476-4922
2538-1911
10.30699/acadpub.mci
en
jalali
1396
7
1
gregorian
2017
10
1
1
Supplement Issue 1: Abstracts of International Tehran Breast Cancer Congress
online
1
fulltext
en
Effect of Six Weeks of Moderate-intensity Aerobic Exercise on Lipid Peroxidation and Antioxidant Status of Women Survived of Breast Cancer
Original/Research Article
Introduction: Oxidative damage is one of the known mechanisms of progression and recurrence<br>
of breast cancer during disease process, radiotherapy and chemotherapy courses,<br>
taking anti-cancer drugs and the loss of aerobic fitness. Therefore, the purpose of this study<br>
was to investigate the effect of six weeks of moderate-intensity aerobic exercise on lipid<br>
peroxidation and antioxidant status of women survived of breast cancer.<br>
Materials and Methods: In this semi experimental study, 19 women survived of breast<br>
cancer with mean age (45.26 ± 2.87 years) and BMI (26.35 ± 2.37 kg/m2) were selected<br>
based on inclusion criteria and then were randomly divided into two control (n = 10)<br>
and experimental (n = 9) groups. Experimental group performed three sessions of aerobic<br>
training at 60-70 HRmax each week and for 6 weeks. The first week trainings, ranging from<br>
60 to 65 HRmax, were conducted, until the end of the fifth week achieved to about 70<br>
HRmax, and at sixth week continued with the same intensity. The control group did not<br>
participate in any exercise program during this period. Blood sampling was conducted 24<br>
hours before the first session and 48 hours after the end of the last training session. The<br>
serum total antioxidant capacity (TAOC) and malondialdehyde (MDA) was measured by<br>
ELISA kits. Data were analyzed by the use of dependent and independent t-test.<br>
Results: A significant reduction in serum levels of MDA and a significant increase in<br>
TAOC was observed in the experimental group (P = 0.003, P = 0.001).Aerobic fitness<br>
improved significantly also (P = 0.001).<br>
Conclusions: Regular moderate-intensity aerobic exercise can prevent the recurrence of<br>
breast cancer by improving the body’s antioxidant defense and aerobic fitness.
Breast Cancer, MDA, TAOC, Moderate-Intensity Aerobic, Exercise
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http://mcijournal.com/browse.php?a_code=A-10-33-81&slc_lang=en&sid=1
Samira
Emadi
1003194753284600869
1003194753284600869
Yes
Akbar
Azamian Jazi
1003194753284600870
1003194753284600870
No
Simin
Hemmati
1003194753284600871
1003194753284600871
No