Multidisciplinary Cancer Investigation
نشریه بین المللی چند تخصصی سرطان
Multidiscip Cancer Investig
Medical Sciences
http://mcijournal.com
1
admin
2476-4922
2538-1911
10.30699/acadpub.mci
en
jalali
1396
7
1
gregorian
2017
10
1
1
Supplement Issue 1: Abstracts of International Tehran Breast Cancer Congress
online
1
fulltext
en
Checking Herbal Products of Resveratrol on Preventing Breast Cancer and Increasing Cell’s Apoptosis
Materials Science and Nanomedicine
Original/Research Article
<div style="text-align: justify;"><strong>Introduction:</strong> Breast cancer is the most common cancer and it is the major reason for death of women’s in the world. Breast cancer is first in four of all female cancers in Iran. It seems herbal products have fewer side effect in curing breast cancer compared with other methods of preventation. Resveratrol is a member of a compounds called polyphenols which are found in herbal products. This study reviews resveratrol effect in preventing breast cancer and increasing cell’s apoptosis.<br>
<strong>Materials and Methods:</strong> This article is a systematic review which has been searched in google scholar and pubmed data base with key words of “resveratrol, breast cancer, apoptosis” until the half of 2016 and then found articles were checked and reviewed.<br>
<strong>Results:</strong> Resveratrol is a polyphenol with the antioxidant properties and with 3.4.5 three hydroxy trans stealen formula which is in many herbal products including grapse, raspberry, berry, peanut, blueberries, etc. resveratrol lead to stop the proliferation of various human tumor lines in vitro’s conditions. Anti-tomors activities of resveratrol is intermediated by several cellural cycles, preventing from proliferation of tumors, inducting apoptosis, decreasing inflammation, and vascularization and preventing from spreading and metastasis and because of height anti-tumor and anti-estrogenic actions it can be a good substituation for Hormone therapy and other ways of preventing breast cancer.<br>
<strong>Conclusions:</strong> Resveratrol in cellular and molecular levels with effects on gene expression can lead to apoptosis and with stimulating lipolysis and inhibiting lipogenesis, can prevent obesity and decrease fat mass which one of the most important risk factors in breast cancer.</div>
Herbal, Resveratrol, Breast Cancer, Cell’s Apoptosis
0
0
http://mcijournal.com/browse.php?a_code=A-10-33-57&slc_lang=en&sid=1
Mohamadali
Mirjalili
10031947532846001071
10031947532846001071
Yes
Amirreza
Rafiei
10031947532846001072
10031947532846001072
No
Amirmohamad
Naghibi
10031947532846001073
10031947532846001073
No