en Supportive and Palliative Care Case Report and Series <div style="text-align: justify;"><strong>Abstract</strong><br> <strong>Introduction: </strong>Extra-nodal exposition of T-cell non-hodgkin lymphoma (NHL) is extremely rare, and is frequently observed in patients with immune system dysfunction. Peripheral T-cell lymphoma does not express CD56 is rare. Malignant lymphoma of the uvula is exceedingly unusual. The current study reported a case of peripheral T-cell lymphoma of the uvula in an immunecompetent patient.<br> <strong>Case presentation: </strong>The current study reported a case of peripheral T-cell lymphoma of the uvula in a 54-year-old male patient. The diagnosis was based on excisional biopsy and ancillary techniques. The patient was referred to the hemato-oncology ward for treatment.<br> <strong>Conclusion: </strong>Considering the fact that the presentation of peripheral T-cell NHL in uvula is uncommon, a high index of suspicion is necessary to diagnose this grave disease. To the best of authors` knowledge, this case is the third case of T-cell lymphoma of the uvula in the English literature.<br> &nbsp;</div> Lymphoma, Uvula, Otolaryngology, Pathology 32 35 http://mcijournal.com/browse.php?a_code=A-10-267-1&slc_lang=en&sid=1 Fariba Binesh binesh44@yahoo.com 10031947532846002015 10031947532846002015 No Department of pathology, Shahid Sadoughi University of medical sciences and health services, Yazd, Iran Hassanali Vahedian Ardakani drvahedian@gmail.com 10031947532846002016 10031947532846002016 No Department of oncology, Shahid Sadoughi University of medical sciences and health services, Yazd, Iran Seyed Hossein Shahcheraghi shahcheraghih@gmail.com 0839552750 10031947532846002017 Yes 3- Department of Modern Sciences & Technologies, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 4- Infectious Diseases Research Center, Shahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran