Multidisciplinary Cancer Investigation
نشریه بین المللی چند تخصصی سرطان
Multidiscip Cancer Investig
Medical Sciences
http://mcijournal.com
1
admin
2476-4922
2538-1911
10.30699/acadpub.mci
en
jalali
1396
1
1
gregorian
2017
4
1
1
2
online
1
fulltext
en
Investigating the Factors Affecting the Mammographic Density of Breast Tissue in Patients Referred to the Breast Cancer Research Center, Iran
Supportive and Palliative Care
Original/Research Article
<p style="text-align: justify;"><strong>Introduction: </strong>Of the factors leading to false negative results in mammography is breast tissue density, and by increasing the density of breast tissue in mammography, the mammography sensitivity decreases. On the other hand, increasing the breast tissue density leads to increased risk of breast cancer. Various factors such as inheritance, genetics, hormonal and reproductive factors, and nutritional factors can affect the breast density, but the definitive cause of this issue is unknown. This study investigated the possible factors influencing the increase in breast tissue density in mammography.<br>
<strong>Methods:</strong> In this cross-sectional study, a total of 428 patients were enrolled; the demographic questionnaire on variables included age, body mass index (BMI), fertility, age of menarche, taking oral contraceptive pills (OCP), menstrual status and breast size, which were completed and evaluated. To determine the relationship between the studied variables and the breast density in mammography, chi-squared test and logistic regression were used.<br>
<strong>Results: </strong>The results showed significant correlation in age of less than 50 years, small breast cup size, low BMI, and the premenopausal status with dense view in mammography (P < 0.001). No significant relationship was observed in OCP consumption and menarche age with dense view in mammography (P > 0.05).<br>
<strong>Conclusions:</strong> Higher breast density in premenopausal women with low BMI may lower the sensitivity of mammography. This can underscore the importance and necessity of further controls with short intervals as well as the use of other tools for diagnosing breast cancer in these groups of patients.</p>
Breast Neoplasms, Mammography, Breast Density.
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http://mcijournal.com/browse.php?a_code=A-10-118-1&slc_lang=en&sid=1
Esmat Alsadat
Hashemi
hashemy1277@yahoo.com
10031947532846001217
10031947532846001217
Yes
Breast Diseases Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR , Tehran, Iran
Shahpar
Haghighat
sha_haghighat@yahoo.com
10031947532846001218
10031947532846001218
No
Quality of life Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR , Tehran, Iran
Asieh
Olfatbakhsh
folfatbakhsh@yahoo.com
10031947532846001219
10031947532846001219
No
Breast Diseases Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR , Tehran, Iran
Hoda
Tafazoli Harandi
h.tafazzoli@gmail.com
10031947532846001220
10031947532846001220
No
Breast Diseases Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR , Tehran, Iran
Toktam
Beheshtian
tbeheshtian@gmail.com
10031947532846001221
10031947532846001221
No
Breast Diseases Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR , Tehran, Iran