Multidisciplinary Cancer Investigation
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Volume 8, Issue 1 (Multidisciplinary Cancer Investigation 2024)
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heydari F, Motamedi Zadeh B, ganjali A, Haghighi G. The Antibacterial properties of psidium guava to eliminate Helicobacter pylori: Preventing Gastric Cancer. Multidiscip Cancer Investig 2024; 8 (1)
URL: http://mcijournal.com/article-1-398-en.html
URL: http://mcijournal.com/article-1-398-en.html
1- Department of Toxicology and Pharmacology, Faculty of Pharmacy, Zabol University of Medical Sciences, Zabol, Iran
2- Department of Epidemiology, Zabol University of Medical Sciences, Iran
3- Food and Drug Deputy, Zabol University of Medical Sciences, Zabol, Iran ,abbasganjali1363@gmail.com
4- Department of Internal Medicine, School of Medicine Zabol University of Medical Sciences, Zabol, Iran
2- Department of Epidemiology, Zabol University of Medical Sciences, Iran
3- Food and Drug Deputy, Zabol University of Medical Sciences, Zabol, Iran ,
4- Department of Internal Medicine, School of Medicine Zabol University of Medical Sciences, Zabol, Iran
Abstract: (2376 Views)
Antibiotic treatment has often failed due to the increased biological resistance of Helicobacter pylori (H. pylori). Therefore, medicinal plants have become necessary to combat this bacteria. This study aims to investigate the antibacterial properties of psidium guava and focus on the effect of the properties of this plant on H. pylori infection to prevent gastric cancer. This study systematically followed the PRISMA guide and searched various international and national databases such as SciELO, PubMed, ProQuest, Google Scholar, Ovid, SID, MediLib, IranDoc, and Cochrane. The search was conducted for articles published in Farsi and English from 2003 to 2023, covering two decades. The search was performed using Persian keywords such as "antibacterial activity," "Psidium guava," and "Helicobacter pylori", as well as their English equivalents and various combinations of these words. The articles were evaluated based on their relevance to the study's purpose without statistical analysis. Out of the 368 selected articles, only nine were deemed final. The results showed that most research was focused on the leaves and fruits of Psidium guava L (PGL). It can be stated that the essential oil of PGL leaves exhibits the most biological activity, and the compounds present in this plant make it a promising candidate for producing drugs with antibacterial activity. PGL plant extracts have appropriate antimicrobial substances that can be used as a pharmaceutical base or a suitable herbal medicine to fight against H. pylori, heal stomach ulcers, and ultimately prevent gastric cancer (GC).
Select article type: Review Article |
Subject:
Prevention, Early Detection and Screening
Received: 2024/06/30 | Accepted: 2024/10/9 | ePublished: 2024/10/23
Received: 2024/06/30 | Accepted: 2024/10/9 | ePublished: 2024/10/23
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