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Yazdani S, Mashhadi A, Bigdeli I, Shahid Sales S. The Unified Protocol for Transdiagnostic Group Treatment of Emotional Disorders [UP] on Depression, Pain Perception, and Cognitive Emotion Regulation in Patients with Cancer. Multidiscip Cancer Investig 2024;
URL: http://mcijournal.com/article-1-397-en.html
1- Department of Psychology, Faculty of Education and Psychology, Ferdowsi University of Mashhad, Mashhad, Iran
2- Department of Psychology, Faculty of Education and Psychology, Ferdowsi University of Mashhad, Mashhad, Iran , mashhadi@um.ac.ir
3- Cancer Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract:   (7 Views)
Introduction: The present study evaluates the efficacy of the Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders (UP) for cancer patients when delivered in a group format.
Materials and Methods: A clinical sample of 38 patients with a cancer diagnosis was enrolled in a randomized control trial (RCT) involving up to 7 sessions of treatment. Patients were randomly assigned to receive treatment with the UP (n=18) and the control group (n=20). The participants in the pre-test and post-test were examined by the Beck Depression Inventory Second Edition (BDI-II), McGill Pain Questionnaire (MPQ), and Cognitive Emotion Regulation Questionnaire (CERQ).
Results: The UP significantly reduced the rate of symptoms of Depression, Pain perception, and maladaptive strategies. Also, a significant increase was shown in adaptive strategies in comparison to participants in the control group.
Conclusions: Results from this RCT provide additional evidence for the efficacy of the UP in reducing symptoms of depression, pain perception, and maladaptive strategies in patients with cancer. Also, this therapy can increase adaptive strategies among these patients.
Full-Text [PDF 456 kb]   (4 Downloads)    
Select article type: Original/Research Article | Subject: Treatment
Received: 2024/09/15 | Accepted: 2024/10/13 | ePublished: 2024/10/24

References
1. Jokar M, Namavari N, Moshiri SA, Jahromi HK, Rahmanian V. The incidence of oral cavity cancer in Iran: A systematic review and meta‐analysis. Cancer Rep. 2023;6[6]:e1836. DOI:10.1002/cnr2.1836. [DOI:10.1002/cnr2.1836] [PMID] [PMCID]
2. Amirkhah R, Naderi-Meshkin H, Mirahmadi M, Allahyari A, Sharifi HR. Cancer statistics in Iran: Towards finding priority for prevention and treatment. Cancer Press J. 2017;3[2]:27-38. DOI: 10.15562/tcp.42. [DOI:10.15562/tcp.42]
3. Roshandel G, Ferlay J, Ghanbari‐Motlagh A, Partovipour E, Salavati F, Aryan K, et al. Cancer in Iran 2008 to 2025: recent incidence trends and short‐term predictions of the future burden. Int J cancer. 2021;149[3]:594-605. DOI: 10.1002/ijc.33574. [DOI:10.1002/ijc.33574] [PMID]
4. Papadopoulou A, Govina O, Tsatsou I, Mantzorou M, Mantoudi A, Tsiou C, et al. Quality of life, distress, anxiety and depression of ambulatory cancer patients receiving chemotherapy. Med Pharm reports. 2022;95[4]:418-29. DOI:10.15386/mpr-2458. [DOI:10.15386/mpr-2458] [PMID] [PMCID]
5. Sourmeh A, Mashhadi A, Sepehri Shamloo Z. The effectiveness of group-based compassion-focused therapy on depression, anxiety and improving the quality of life in women with feminine cancers. Int multispecialty J cancer. 2020;4[2]:21-7. DOI:10.30699/mci/4.2.21. [DOI:10.30699/mci.4.2.21]
6. Krebber AMH, Buffart LM, Kleijn G, Riepma IC, De Bree R, Leemans CR, et al. Prevalence of depression in cancer patients: a meta‐analysis of diagnostic interviews and self‐report instruments. Psycho‐Oncology. 2014;23[2]:121-30. DOI: 10.1002/pon.3409. [DOI:10.1002/pon.3409] [PMID] [PMCID]
7. Pirl WF. Evidence report on the occurrence, assessment, and treatment of depression in cancer patients. JNCI Monogr. 2004;2004[32]:32-9. DOI: 10.1093/jncimonographs/lgh026. [DOI:10.1093/jncimonographs/lgh026] [PMID]
8. Naser AY, Hameed AN, Mustafa N, Alwafi H, Dahmash EZ, Alyami HS, et al. Depression and anxiety in patients with cancer: a cross-sectional study. Front Psychol. 2021;12:585534. DOI: 10.3389/fpsyg.2021.585534. [DOI:10.3389/fpsyg.2021.585534] [PMID] [PMCID]
9. Pereira MG, Figueiredo AP, Fincham FD. Anxiety, depression, traumatic stress and quality of life in colorectal cancer after different treatments: A study with Portuguese patients and their partners. Eur J Oncol Nurs. 2012;16[3]:227-32. DOI: 10.1016/j.ejon.2011.06.006. [DOI:10.1016/j.ejon.2011.06.006] [PMID]
10. Vaziri ZS, Mashhadi A, Shamloo ZS, Shahidsales S. Mindfulness-based cognitive therapy, cognitive emotion regulation and clinical symptoms in females with breast cancer. Iran J Psychiatry Behav Sci. 2017;11[4]:e4158. DOI: 10.5812/ijpbs.4158. [DOI:10.5812/ijpbs.4158]
11. Wu IHC, Balachandran DD, Faiz SA, Bashoura L, Escalante CP, Manzullo EF. Characteristics of cancer-related fatigue and concomitant sleep disturbance in cancer patients. J Pain Symptom Manage. 2022;63[1]:e1-8. DOI:10.1016/j.jpainsymman.2021.07.025. [DOI:10.1016/j.jpainsymman.2021.07.025] [PMID] [PMCID]
12. Burz C, Costin C, Pop V, Balacescu L, Bujor A, Cismaru A, et al. Psychological disorders in relation to pain syndrome in patients with colorectal cancer. J Med Brasovean. 2018;1[1]:106-14.
13. Van Den Beuken-Van MH, Hochstenbach LMJ, Joosten EAJ, Tjan-Heijnen VCG, Janssen DJA. Update on prevalence of pain in patients with cancer: systematic review and meta-analysis. J Pain Symptom Manage. 2016;51[6]:1070-90. DOI:10.1016/j.jpainsymman.2015.12.340. [DOI:10.1016/j.jpainsymman.2015.12.340] [PMID]
14. Lokapur M, Kumar N, Shah H, Shah D. A review of chronic pain with depression and/or anxiety comorbidities in the Indian population. Indian J Pain. 2023;37[1]:3-12. DOI:10.4103/ijpn.ijpn_26_21 [DOI:10.4103/ijpn.ijpn_26_21] [PMCID]
15. Miller LR, Cano A. Comorbid chronic pain and depression: who is at risk? J pain. 2009;10[6]:619-27. DOI: 10.1016/j.jpain.2008.12.007. [DOI:10.1016/j.jpain.2008.12.007] [PMID]
16. Smith IS, Bind M, Weihs KL, Bei B, Wiley JF. Targeting emotional regulation using an Internet‐delivered psychological intervention for cancer survivors: A randomized controlled trial. Br J Health Psychol. 2023;28[4]:1185-205. DOI: 10.1111/bjhp.12679. [DOI:10.1111/bjhp.12679] [PMID] [PMCID]
17. Brandão T, Tavares R, Schulz MS, Matos PM. Measuring emotion regulation and emotional expression in breast cancer patients: A systematic review. Clin Psychol Rev. 2016;43:114-27. DOI: 10.1016/j.cpr.2015.10.002. [DOI:10.1016/j.cpr.2015.10.002] [PMID]
18. Su C-H, Liu Y, Hsu H-T, Kao C-C. Cancer fear, emotion regulation, and emotional distress in patients with newly diagnosed lung cancer. Cancer Nurs. 2024;47[1]:56-63. DOI:10.1097/NCC.0000000000001150. [DOI:10.1097/NCC.0000000000001150] [PMID]
19. Mendoza ME, Capafons A, Gralow JR, Syrjala KL, Suárez‐Rodríguez JM, Fann JR, et al. Randomized controlled trial of the Valencia model of waking hypnosis plus CBT for pain, fatigue, and sleep management in patients with cancer and cancer survivors. Psycho‐oncology. 2017;26[11]:1832-8. DOI: 10.1002/pon.4232. [DOI:10.1002/pon.4232] [PMID] [PMCID]
20. Schaeuffele C, Schulz A, Knaevelsrud C, Renneberg B, Boettcher J. CBT at the crossroads: The rise of transdiagnostic treatments. Int J Cogn Ther. 2021;14:86-113. DOI: 10.1007/s41811-020-00095-2. [DOI:10.1007/s41811-020-00095-2]
21. Osma J, Martínez-García L, Quilez-Orden A, Peris-Baquero Ó. Unified protocol for the transdiagnostic treatment of emotional disorders in medical conditions: A systematic review. Int J Environ Res Public Health. 2021;18[10]:5077. DOI:10.3390/ijerph18105077. [DOI:10.3390/ijerph18105077] [PMID] [PMCID]
22. Barlow DH, Farchione TJ, Bullis JR, Gallagher MW, Murray-Latin H, Sauer-Zavala S, et al. The unified protocol for transdiagnostic treatment of emotional disorders compared with diagnosis-specific protocols for anxiety disorders: A randomized clinical trial. JAMA psychiatry. 2017;74[9]:875-84. DOI:10.1001/jamapsychiatry.2017.2164. [DOI:10.1001/jamapsychiatry.2017.2164] [PMID] [PMCID]
23. Cohen J. Statistical power analysis for the behavioral sciences. routledge; 2013. DOI: 10.4324/9780203771587. [DOI:10.4324/9780203771587]
24. Beck AT. Manual for the beck depression inventory-II. Psychol Trauma Theory, Res Pract Policylogical Corp. 1996;82. [DOI:10.1037/t00742-000]
25. Ghassemzadeh H, Mojtabai R, Karamghadiri N, Ebrahimkhani N. Psychometric properties of a Persian‐language version of the Beck Depression Inventory‐Second edition: BDI‐II‐PERSIAN. Depress Anxiety. 2005;21[4]:185-92. DOI: 10.1002/da.20070. [DOI:10.1002/da.20070] [PMID]
26. Melzack R. The McGill Pain Questionnaire: major properties and scoring methods. Pain. 1975;1[3]:277-99. DOI: 10.1016/0304-3959[75]90044-5. [DOI:10.1016/0304-3959(75)90044-5] [PMID] [PMCID]
27. Ngamkham S, Vincent C, Finnegan L, Holden JE, Wang ZJ, Wilkie DJ. The McGill Pain Questionnaire as a multidimensional measure in people with cancer: an integrative review. Pain Manag Nurs. 2012;13[1]:27-51. DOI: 10.1016/j.pmn.2010.12.003. [DOI:10.1016/j.pmn.2010.12.003] [PMID] [PMCID]
28. Khosravi M, Sadighi S, Moradi S, Zendehdel K. Translation, adaptation and reliability of Persian-McGill Pain Questionnaire [P-MPQ] in Iranian cancer patients. Basic Clin Cancer Res. 2014;6[3]:12-17.
29. Garnefski N, Kraaij V, van Etten M. Specificity of relations between adolescents' cognitive emotion regulation strategies and internalizing and externalizing psychopathology. J Adolesc. 2005;28[5]:619-31. DOI:10.1016/j.adolescence.2004.12.009. [DOI:10.1016/j.adolescence.2004.12.009] [PMID]
30. Wang Y, Yi J, He J, Chen G, Li L, Yang Y, et al. Cognitive emotion regulation strategies as predictors of depressive symptoms in women newly diagnosed with breast cancer. Psycho‐Oncology. 2014;23[1]:93-9. DOI: 10.1002/pon.3376. [DOI:10.1002/pon.3376] [PMID]
31. Hasani J. Persian Version of the emotion regulation questionnaire: factor structure, reliability and validity. Int J Behav Sci. 2016;10[3]:108-13.
32. Ito M, Horikoshi M, Kato N, Oe Y, Fujisato H, Yamaguchi K, et al. Efficacy of the unified protocol for transdiagnostic cognitive-behavioral treatment for depressive and anxiety disorders: a randomized controlled trial. Psychol Med. 2023;53[7]:3009-20. DOI:10.1017/S0033291721005067. [DOI:10.1017/S0033291721005067] [PMID] [PMCID]
33. Sauer-Zavala S, Bentley KH, Steele SJ, Tirpak JW, Ametaj AA, Nauphal M, et al. Treating depressive disorders with the Unified Protocol: A preliminary randomized evaluation. J Affect Disord. 2020;264:438-45. DOI: 10.1016/j.jad.2019.11.072. [DOI:10.1016/j.jad.2019.11.072] [PMID] [PMCID]
34. Longley SL, Gleiser TS. Efficacy of the Unified Protocol: A systematic review and meta-analysis of randomized controlled trials. Clin Psychol Sci Pract. 2023;30[2]:208-21. DOI: 10.1016/j.cpr.2019.101751. [DOI:10.1016/j.cpr.2019.101751] [PMID]
35. Harel K, Czamanski-Cohen J, Cohen M, Weihs KL. Emotional Processing, Coping, and Cancer-Related Sickness Symptoms in Breast Cancer Survivors: Cross-Sectional Secondary Analysis of the REPAT Study. Res Sq. 2023; DOI: 10.21203/rs.3.rs-3164706/v1. [DOI:10.21203/rs.3.rs-3164706/v1]
36. Boswell JF, Anderson LM, Barlow DH. An idiographic analysis of change processes in the unified transdiagnostic treatment of depression. J Consult Clin Psychol. 2014;82[6]:1060. DOI: 10.1037/a0037403. [DOI:10.1037/a0037403] [PMID]
37. Allen LB, Tsao JCI, Seidman LC, Ehrenreich-May J, Zeltzer LK. A unified, transdiagnostic treatment for adolescents with chronic pain and comorbid anxiety and depression. Cogn Behav Pract. 2012;19[1]:56-67. DOI: 10.1016/j.cbpra.2011.04.007. [DOI:10.1016/j.cbpra.2011.04.007] [PMID] [PMCID]
38. Kamalinedjad F, Talaei A. Effectiveness of Integrated TransDiagnostic Group Therapy in Reducing Symptoms of Chronic Pain, Depression, and Anxiety among Cancer Patients. Int J Body, Mind Cult. 2023;10[3]:355-65. DOI: 10.22122/ijbmc.vi.468.
39. Garland EL, Howard MO. Mindfulness-oriented recovery enhancement reduces pain attentional bias in chronic pain patients. Psychother Psychosom. 2013;82[5]:311-18. DOI: 10.1159/000348868. [DOI:10.1159/000348868] [PMID]
40. Chiesa A, Serretti A. Mindfulness-based interventions for chronic pain: a systematic review of the evidence. J Altern Complement Med. 2011;17[1]:83-93. DOI: 10.1089/acm.2009.0546. [DOI:10.1089/acm.2009.0546] [PMID]
41. Mazaheri M, Daghaghzadeh H, Afshar H, Mohammadi N. The effectiveness of the unified protocol on emotional dysregulation and cognitive emotion regulation strategies in patients with psychosomatic disorders. Int J Body, Mind Cult. 2014;1[1]:73-82. DOI: 10.22122/ijbmc.v1i1.7.
42. Bameshgi M, Kimiaei A, Mashhadi A. Effectiveness of a unified protocol on emotion regulation and experiential avoidance in women with comorbid major depressive and generalized anxiety symptoms. J Fundam Ment Heal. 2020;22[6]:341-48. DOI:10.22038/JFMH.2020.17559.
43. Rahimi F, Mashhadi A, Hosseinzadeh Maleki Z. Applying the unified protocol for transdiagnostic treatment of emotional disorders [UP] on emotional regulation, cognitive flexibility, mindful emotional awareness and quality of life in breast cancer: A pilot study. Multidiscip Cancer Investig. 2023;7[2]:19-29. DOI:10.30699/mci.7.4.392-2

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